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SpecialistBase2026 Compliant

CPT 67028

2026 Billing Guide

Intravitreal Injection

Reimbursement

$157.31

Threshold

N/A

2026 Status

Active

What is CPT Code 67028?

CPT 67028 is defined as: The injection of a pharmacologic agent (such as anti-VEGF medications, steroids, or antibiotics) into the vitreous body of the eye. This procedure is commonly used to treat retinal diseases including age-related macular degeneration (AMD), diabetic retinopathy, and retinal vein occlusion. It is a 'separate procedure' when performed as the only surgical service, but it is often billed with a separate J-code for the medication.

This code is primarily used for Specialist services. It falls under the category of Surgery / Eye and Ocular Adnexa and is valid for the 2026 calendar year according to the CMS Physician Fee Schedule.

2026 RVU Components

Relative Value Units (Non-Facility)

Standard Formula Applied

Work RVU

1.46

Physician Effort

PE (Non-Fac)

3.1

Practice Expense

Malpractice

0.15

Risk Factor

Total RVU

4.71

Note: [(Work RVU * Work GPCI) + (PE RVU * PE GPCI) + (MP RVU * MP GPCI)] * Conversion Factor

2026 CMS Policy Intelligence

efficiency adjustment

Subject to -2.5% Efficiency Adjustment. CMS assumes that the standardization of injection protocols and the high volume of these procedures in specialized clinics have reduced the average physician work time per injection.

conversion factor

Utilizes the 2026 Non-QP baseline of $33.40.

drug payment reform

Monitor CMS 'Part B Drug' policy changes in 2026, as reimbursement for the high-cost medications used with 67028 may be subject to separate inflationary caps.

Administrative Framework

Global Period

000 (0 Days)

Place of Service

11 (Office)22 (Outpatient Hospital)

NCCI Exclusions

Do not bill with:65235670156703692002-9201499211-99215

Key Modifiers

25Significant, separately identifiable E/M service. Required if an E/M is performed on the same day for a different reason or if the decision to perform the first injection in a series is made.
50Bilateral procedure. Check specific payer rules; many Medicare MACs prefer RT/LT modifiers over 50 for ocular injections.

Operational Requirements

drug j codes

The cost of the medication (e.g., Eylea, Lucentis, Avastin) is NOT included in 67028 and must be billed using the specific J-code (e.g., J0178, J2778) and appropriate dosage units.

site documentation

The procedure note must specify the site (intravitreal) and the lateralization (Right, Left, or Both).

waste documentation

If a single-use vial is used and there is leftover medication, use Modifier JW (Waste) on a separate line to bill for the discarded amount, as required by CMS.

supply billing

Most supplies used (needles, syringes, drapes) are included in the PE portion of 67028 and cannot be billed separately.

Compliance Checklist

Detailed time tracking (cumulative for the month).
Specific clinical decision-making documentation.
Electronic care plan availability and access log.

Audit Defense

No specific audit defense elements defined.

2026 Update

Work RVU reduced by 2.5% efficiency adjustment. National payment for the professional service is ~$117.57.

Common Clinical Scenarios

No clinical examples provided.

Target Specialties & Utilization

OphthalmologyRetina Specialists

Typical Clinical Indications (ICD-10)

H35.3212 (Exudative age-related macular degeneration, right eye, with active choroidal neovascularization)E11.3511 (Type 2 diabetes mellitus with proliferative diabetic retinopathy with macular edema, right eye)

Frequently Asked Questions

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